Dr. Joerg Dreessen Novartis Institutes for Biomedical Research, Discovery Technologies / DTI, Basel, Switzerland was awarded "Best Poster" at the annual meeting of the Society for Biomolecular screening in Orlando Florida.  Dr. Dreessen's Poster " Rapid Homogenization of Single Step Dilutions, in Miniaturized 1,536 MTP Liquid Handling" described using a V&P pin tool and an orbital shaker to to transfer and mix solutions in a 1,536 Microplate.  The Poster was also accompanied by a movie that we have placed on the web.  Poster Abstract:

Assay miniaturization into 1536MTP, accompanied with low volume handling, is one important step in pharmaceutical industry on increasing the probability in finding novel biologically active molecular
entities by continuously increased HTS. This volume range (nano- to microliter) is physically a challenge (surface tension, diffusion, evaporation, viscosity, factored by surface/volume ratio).

Unlike other low volume liquid handlers, pin tools provide the opportunity in low relative dead volume to transfer compound solution directly from stock to assay. High speed video visualization of the compound transfer (will be presented) revealed localized inhomogeneous high compound/DMSO concentrations in the assay volume, which could end up in misleading results, especially in cellular assays.

A recently launched high frequency shaker prototype has been improved in collaboration with a leading manufacturer for a) mixing efficiency and b) use in fully automated systems, resulting in homogeneous distribution of compound/DMSO in a 1536MTP well in fractions of a second. 

V&P Scientific was awarded US patent #6,692,701 for the Manual Compact Disc Arrayer used to make arrays of DNA, RNA, protein, antibody, antigen and other materials on a compact disc.  This device is simple and inexpensive enough so even small labs can make their own arrays, and the method rapid enough that larger labs will use it to expedite results or use it produce pilot data.

September 2, 2003

V&P Scientific was awarded US patent #6,613,284 for the Manual Glass Slide Arrayer used to make arrays of DNA, RNA, protein, antibody, antigen and other materials on a variety of different surfaces.  This device is simple and inexpensive enough so even small labs can make their own arrays, and the method rapid enough that larger labs will use it to expedite results or use it produce pilot data.

August 1, 2003

VP 755C-384B is a 384 Bubble Paddle Mixing Reservoir that keeps cells and beads in homogeneous suspension while pipetting.  Its unique heat transfer system keeps beads cold or cells warm  and its small footprint makes it workstation friendly.

June 30, 2003

VP 581 Warped PCR plate flattener. The VP 581 is designed with a groove in 3 sides that capture the lip of a warped PCR plate. Simply slide the plate in from the open side and the plate is flattened. Problem solved no more tip crashes!

June 9, 2003

Multiplexing assays with a pin tool. Liquid to dry plate transfers to make mini-microarrays in a single well for multiplexing assays.

May 29, 2003

April 3, 2003

January 10, 2003

December 15, 2002

V&P Scientific was awarded US patent #6,461,034 for the Bubble Paddle Stirrer for hard to suspend particulates, cells, and beads.

March 19, 2002

V&P Scientific was awarded US patent #6,357,907 for the Magnetic Levitation Stirrer for deep well microplates. The Magnetic Levitation Stirrer will mix thousands of deep wells or vials at the same time. It is particularly effective in mixing viscous slurries.

January 23, 2001

V&P Scientific was awarded patent # 6,176,609 for the Alligator Tumble Stir Device and method.  The Tumble Stirrer will mix thousands of vessels or microplates at the same time.